Sofia Crespo transforms her interest in biotechnology into works of art, considering the ways in which organic life mimics and utilizes artificial mechanisms. Such a thematic concern is also reflected in Garden Cartography, which combines cyanotype and blockchain, artistic mediums that are diametrically opposed in their historical context—while cyanotype was discovered in the mid-19th Century as one of the first historical examples that facilitated the development of film photography, blockchain is the latest technology to be adopted within the world of contemporary art through the incorporation of Non-Fungible Tokens (NFTs).

Crespo nonetheless avoids such a facile juxtaposition between the old and the new, since the cyanotype print, produced in blue that is characteristic to the medium, is in fact created through using Convolutional Neural Network, an artificially produced network that was initially developed from machine learning. In so doing, she posits that nature and artifice cannot be so easily separated, even though they are almost always construed as oppositional and incompatible notions.